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PHARMACEUTICAL INTERMEDIATES

Our range of pharmaceutical intermediates represent the culmination of an unwavering dedication to excellence, innovation, and sustainability. With a deep commitment to quality and innovation, we offer a diverse portfolio of intermediates that play a crucial role in the production of life-saving pharmaceuticals.

  • Meeting the Highest Standards of Quality
  • Impurity Profiles Identified and Characterised
  • Synergistic Range of End-Use API’s

Our Products

Product Name Target API Chemicals Names
DTBA CAS Number 119-80-2 Quetiapine Fumarate
Axitinib
Ziprasidone
2,2’-dithiodibenzoic Acid
2,2-Dithiosalicylic acid
2-Carboxyphenyl disulfide
Bis(2-carboxyphenyl) disulfide
2-CTX CAS Number 86-39-5 Chlorprothixene 2-chlorothioxanthone
2-Chlorothioxanthen-9-one
2-Chloro-9H-thioxanthen-9-one
MMBA CAS Number 20054-45-9 Axitinib 2-mercapto-n-methylbenzamide
N-methyl-2-sulfanylbenzamide
PIP BIT CAS Number 87691-88-1 Ziprasidone 3-Piperazinobenzisothiazole hydrochloride
3-(Piperazin-1-yl)benzo[d]isothiazole hydrochloride
3-Piperazinyl-1,2-Benzisothiazole Hydrochloride
OTBN CAS Number 114772-53-1 Angiotensin
Receptor Blockers
2-cyano-4-methylbiphenyl
4'-Methyl-2-cyanobiphenyl
2-(4-methylphenyl)benzonitrile
4'-Methylbiphenyl-2-carbonitrile
Bromo-OTBN CAS Number 114772-54-2 Angiotensin
Receptor Blockers
4-bromomethyl-2-cyanobiphenyl
2-[4-(bromomethyl)phenyl]benzonitrile
4'-(bromomethyl)-[1,1'-biphenyl]-2-carbonitrile
2-Cyano-4'-bromomethylbiphenyl
DBTP CAS Number 111974-74-4 Quetiapine Fumarate 11-Piperazinodibenzo[b,f][1,4]thiazepine
dihydrochloride
Norquetiapine dihydrochloride
Dibenzo[b,f][1,4]thiazepine, 11-(1-piperazinyl)-,
dihydrochloride

FAQ'S

1. What are the benefits of using angiotensin receptor blockers?

Angiotensin receptor blockers (ARBs) are a class of medications that are commonly used to treat hypertension (high blood pressure), heart failure, and other cardiovascular conditions. Here are some potential benefits of using ARBs:

  1. Lower blood pressure: ARBs work by blocking the action of angiotensin II, a hormone that can cause blood vessels to narrow and increase blood pressure. By blocking this hormone, ARBs can help to lower blood pressure.
  2. Protect the heart and kidneys: ARBs have been shown to have protective effects on the heart and kidneys. They can help to reduce the risk of heart failure and kidney damage in patients with hypertension and other cardiovascular conditions.
  3. Improve symptoms: In patients with heart failure, ARBs can help to reduce symptoms such as shortness of breath and fatigue.
  4. Well-tolerated: ARBs are generally well-tolerated, with few side effects. They are considered to be safer than some other medications that are commonly used to treat hypertension, such as beta blockers.
  5. May have additional health benefits: Some studies have suggested that ARBs may have additional health benefits, such as reducing the risk of stroke and dementia.

2. What are the effective anti breast cancer drugs like axitinib?

Axitinib is not typically used as a treatment for breast cancer. However, there are several other effective drugs that are commonly used to treat breast cancer. Here are some examples:

  1. Tamoxifen: This is a selective estrogen receptor modulator (SERM) that is used to treat hormone receptor-positive breast cancer. It works by blocking the action of estrogen in the body.
  2. Aromatase inhibitors (AI): AIs are another type of hormone therapy that are used to treat hormone receptor-positive breast cancer. They work by blocking the enzyme aromatase, which converts androgens to estrogen.
  3. Trastuzumab: This is a monoclonal antibody that is used to treat HER2-positive breast cancer. It works by targeting the HER2 protein, which is overexpressed in some types of breast cancer.
  4. Pertuzumab: This is another monoclonal antibody that is used to treat HER2-positive breast cancer. It works by blocking the interaction between HER2 and other proteins that promote cancer growth.
  5. Chemotherapy: Chemotherapy is a type of cancer treatment that uses drugs to kill rapidly dividing cancer cells. It can be used to treat many different types of breast cancer.
  6. CDK4/6 inhibitors: These are a relatively new class of drugs that are used to treat hormone receptor-positive and HER2-negative breast cancer. They work by inhibiting the activity of cyclin-dependent kinases 4 and 6, which play a role in cell division.

3. Which are the most effective antipsychotic drugs available?

There is no single "most effective" antipsychotic drug, as the choice of medication depends on the individual patient's symptoms, medical history, and other factors. However, here are some examples of commonly used antipsychotic drugs and their general effectiveness:

  1. Second-generation antipsychotics (SGAs): These medications are also known as atypical antipsychotics and are generally considered to be more effective than first-generation antipsychotics (FGAs) for treating schizophrenia and other psychotic disorders. Examples of SGAs include risperidone, olanzapine, quetiapine, aripiprazole, and clozapine.
  2. Clozapine: This is a particularly effective medication for treatment-resistant schizophrenia, which does not respond to other medications. However, it can have serious side effects, including agranulocytosis (a decrease in white blood cells).
  3. Aripiprazole: This medication is used to treat schizophrenia, bipolar disorder, and major depressive disorder. It has a lower risk of causing weight gain and metabolic side effects than some other antipsychotics.
  4. Lurasidone: This medication is used to treat schizophrenia and bipolar disorder. It has a relatively low risk of causing metabolic side effects and can be taken with or without food.
  5. Olanzapine: This medication is used to treat schizophrenia and bipolar disorder. It can be effective in treating both positive and negative symptoms of schizophrenia but can cause significant weight gain and metabolic side effects.

4. What chemicals are used in hand sanitizers?

Hand sanitizers contain a variety of chemicals that are effective in killing or reducing the number of microorganisms on hands. Here are some examples of chemicals commonly used in hand sanitizers:

  1. Alcohol: The most commonly used active ingredient in hand sanitizers is ethyl alcohol (ethanol) or isopropyl alcohol. These alcohols are effective against a wide range of bacteria and viruses.
  2. Hydrogen peroxide: Some hand sanitizers may contain hydrogen peroxide, which can help to kill or reduce the number of microorganisms on hands.
  3. Quaternary ammonium compounds: Examples include benzalkonium chloride and benzethonium chloride. These are less commonly used in hand sanitizers but can be effective against some bacteria and viruses.
  4. Triclosan: This is an antibacterial agent that was once commonly used in hand sanitizers, but has been banned by the FDA due to concerns about its safety and effectiveness.
  5. Fragrances and moisturizers: Hand sanitizers may also contain fragrances and moisturizing agents to improve their scent and texture.

It's important to carefully follow the instructions on hand sanitizer product labels, including using the recommended amount and rubbing the sanitizer into your hands until they are dry. Additionally, hand sanitizers should be stored out of reach of children and away from heat sources, as they may be flammable.

5. What is the active ingredient in Dettol?

The active ingredient in Dettol is chloroxylenol (C8H9ClO), which is a chemical compound with antimicrobial properties. Chloroxylenol is effective against a wide range of bacteria and viruses, and is commonly used as an ingredient in disinfectants, antiseptics, and sanitizers. In Dettol, chloroxylenol is present in a concentration of 4.8%.

6. What chemicals are used in antiseptic soaps?

Antiseptic soaps are designed to kill or reduce the number of microorganisms on the skin. Here are some examples of chemicals commonly used in antiseptic soaps:

  1. Triclosan: This was once a commonly used active ingredient in antiseptic soaps, but it has been banned by the FDA due to concerns about its safety and effectiveness.
  2. Chlorhexidine gluconate: This is a chemical compound with antimicrobial properties that is commonly used in antiseptic soaps and hand sanitizers.
  3. Benzalkonium chloride: This is a quaternary ammonium compound that is commonly used in antiseptic soaps, hand sanitizers, and surface disinfectants.
  4. Ethyl alcohol: This is a common active ingredient in hand sanitizers, but it can also be found in some antiseptic soaps.
  5. Iodine: Povidone-iodine is a common antiseptic agent that is sometimes used in antiseptic soaps.
  6. Hydrogen peroxide: This is sometimes used in antiseptic soaps as a disinfectant agent.

It's important to carefully follow the instructions on antiseptic soap product labels, including using the recommended amount and rubbing the soap into your skin for the recommended length of time. Additionally, antiseptic soaps may not be suitable for all skin types, and may cause irritation or dryness in some individuals. If you experience any adverse reactions after using an antiseptic soap, you should discontinue use and consult a healthcare professional.

CERTIFIED FOR
EXCELLENCE

Cerigo is proud to hold ISO certifications that underscore our commitment to quality, environmental responsibility, and workplace safety. With EN ISO 9001:2015, EN ISO 14001:2015, ISO 45001:2015 we ensure that our products meet the highest quality standards through minimal environmental impact and an unwavering commitment to the safety and well-being of our employees.

ISO CERTIFICATION

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